Movement Disorders (revue)

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Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI).

Identifieur interne : 000311 ( Main/Exploration ); précédent : 000310; suivant : 000312

Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI).

Auteurs : Mike A. Nalls [États-Unis] ; Margaux F. Keller [États-Unis] ; Dena G. Hernandez [États-Unis] ; Lan Chen [États-Unis] ; David J. Stone [États-Unis] ; Andrew B. Singleton [États-Unis]

Source :

RBID : pubmed:26268663

Abstract

The Parkinson's Progression Marker Initiative is an international multicenter study whose main goal is investigating markers for Parkinson's disease (PD) progression as part of a path to a treatment for the disease. This manuscript describes the baseline genetic architecture of this study, providing not only a catalog of disease-linked variants and mutations, but also quantitative measures with which to adjust for population structure.

DOI: 10.1002/mds.26374
PubMed: 26268663


Affiliations:


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